CLT 140 - Immunology
An introduction to basic concepts in immunology. Topics include classification systems of the immune system. Functions and interactions of each component of the immune subsystems. Mechanisms of action of each active component of the immune subsystems. Detailed analysis of the development of the immune system, specific immunoglobulin structures, functions and genetics, complement and other cascades and the major histocompatibility complex will be covered. Disorders discussed will include anergy, hypersensitivities, autoimmune diseases, allergies, immune deficiencies and AIDS. Two class hours.
Prerequsite(s): CLT 100 with a grade of C or higher AND any one of BIO 134, BIO 142, BIO 144 each with a grade of C or higher; or permission of instructor. Co-requisite(s): CLT 145 AND any one of BIO 135, BIO 143, BIO 145 (or previously completed)
Course Learning Outcomes
1. Describe the similarities and differences between the innate and acquired immune systems.
2. Compare and contrast primary and secondary immune responses.
3. Compare and contrast the five classes of immunoglobulins in terms of structure or function.
4. Summarize the role of MHC molecules and T cell subsets in the adaptive immune response.
5. Describe the three pathways of complement activation.
6. Compare and contrast the four types of hypersensitivity reactions.
7. Evaluate the significance of multiple laboratory test results in the diagnosis of systemic autoimmune disease.
8. Provide examples of organ-specific autoimmunity resulting from cell-mediated or antibody-mediated pathologies.
9. Discuss appropriate methods to diagnose immunoproliferative or immunodeficiency disorders.
10. Distinguish between acute or chronic diseases caused by different viruses on the basis of serology.
11. Compare and contrast serological testing for bacterial infections such as syphilis and Lyme disease.
12. Describe appropriate serological testing methods for fungal or parasite infections.
Course Offered Spring only