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Course Descriptions

CHE 252 - Organic Chemistry II

5 Credits

This is the second semester of a two-semester sequence in organic chemistry. The principles of bonding, molecular structure (with an emphasis on the three-dimensional aspects of structure and stereochemistry), polarities and acid-base properties introduced in CHE 251 are extended and related to additional types of organic compounds and their reactions. The course concentrates on organic reactions and their mechanisms. The relationship between molecular structure, properties, and reactivity is emphasized throughout the course. Major topics discussed include: reactions of dienes; substitution and elimination reactions; free radical reactions; and nucleophilic addition, substitution, and condensation reactions of carbonyl compounds. If time permits, special topics such as polymers and biomolecules will also be discussed.

The laboratory continues and builds on the basic separation, purification, synthesis and structure determination techniques of organic chemistry on the microscale level introduced in the CHE 251 laboratory. Spectroscopic methods of analysis are also emphasized in CHE 252. In addition to the ultraviolet/visible (UV/Vis), infrared (IR), and proton nuclear magnetic resonance (1H-NMR) spectroscopic methods introduced in CHE 251, carbon nuclear magnetic resonance (13C-NMR) and mass spectroscopy (MS) are also discussed and used in the CHE 252 laboratory.

Prerequisite: CHE 251 with a grade of C- or higher, or permission of instructor.

MCC General Education: MCC-TL - Technological Literacy (MTL)

Course Learning Outcomes
1. Assign IUPAC names to simple aromatic compounds, amines, carboxylic acid derivatives, aldehydes, and ketones. Draw the structure of an aromatic compound, amine,carboxylic acid derivative, aldehydes, or ketone from an IUPAC name.
2. Predict reaction products of an organic reaction from given starting materials and reagents.
3. Provide the necessary starting material and/or reagents required to produce a given organic product.
4. Assess and predict the relationship between the structure of an organic compound and its chemical properties and reactivity.
5. Design multistep (5-10 steps) synthesis for organic compounds using retrosynthetic analysis.
6. Propose reasonable reaction mechanisms for a given reaction using curved arrow notation.
7. Generate the complete structure of moderately complex unknown organic compounds using UV/Vis, IR, proton and carbon-13 NMR spectroscopy, and mass spectrometry.
8. Perform microscale organic reactions and determine product identity, purity and percent yield.
9. Determine the identity of an unknown liquid and solid using various experimental techniques learned during the course of the year.
10. Write formal lab reports to convey results of experiments in a clear, logical manner.

Course Offered Spring

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Fall Semester 2022
Summer Session 2022